Lifestyle
changes have welcomed various health concerns like overweight, reduced bone
density, infertility, etc.; which are indeed responsible for variety of
underlying dangerous conditions such as arthritis. It has been estimated that
around 50% people, over the age 65 can have arthritis. Hence, in developed
countries, arthritis can be one of the leading health issues, which need to be
tackled well within time to avoid increased social economic burden.
Arthritis can be
categorized as an inflammatory, joint disorder; affecting multiple joints at a
time. The condition has more than 100 subdivisions, with osteoarthritis and
rheumatoid arthritis as the most common forms. It is simply known to be a
slowly progressive disease, affecting persons of any age groups; although women
are known to be more prevalent than men.
Our joints are
made up of joining of two bones to allow easy movement. These joints are being
protected with the underlying tissue named, cartilages. The cartilages are
soft, spongy tissues; acting as beds in between the two bones. Due to the
presences of these tissues, the friction between the two bones is reduced,
while joints are in mobile state. The cartilages are as well supported with the
presence of synovial fluid, which is helpful in shock absorption. Thus, the
entire assembly can access an easy and long term functionality of joints.
However, variety of issues such as obesity, smoking, poor diet, etc. can create
non significant inflammatory responses, which can degenerate these supportive
tissues such as cartilages and synovial fluid; exposing bones to outer shocks
and friction, leading to their damage.
Stem cells are the young, privileged cells with the capacity to differentiate
into cells of different origin. The property of stem cells can be uniquely
identified to be potential treatment for arthritis patients. Autologous stem
cells isolated from two different sources such as adipose tissue and/or bone
marrow can provide mesenchymal and hematopoietic stem cells in abundance. These
stem cells are enriched in the laboratory and infused back in the patient’s
joints to avail maximum benefits of tissue function restoration. Once inside
the body, these stem cells are known to reach at the site of injury, due to
their strong communication pathways with other cells, secrete growth factors to
reduce the inflammation and elicit strong immunological reactions to speed up
the process of healing. Stem cells, in case of joints problems or arthritis are
known to induce cells of Chondrocytes origin and get differentiated into
cartilages. Once differentiated into cartilages, there can be reduced friction
and pain associated with OA.
Thus,
considering their anti-inflammatory and regenerative capacities; there are
pretty good reasons to say that these stem cells can be good candidates for
treatment.
I am really grateful to you for giving these information on stem cells arthritis treatment. I was in badly need for these since my mother is a arthritis patient. We will be giving her this treatment since there are positive feedback of it.
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