Stem Cell Treatment for Osteoarthritis

Osteoarthritis is  the most common form of artheritis, usual form of chronic disorder  related to the joints that is found in millions of people all across the globe. It is also know as degenerative  joint disease or degenerative artheritis that takes place due to the brek down joint cartilage and the underlying bone. OA can affect any joint, but it occurs most often in knees, hips, lower back and neck, small joints of the fingers and the bases of the thumb and big toe.

Due to the breakdown of the cartilage, pain, selling up and discomfort in the movemnt of the joint is noticed and it can be seen in all age group and genders, however older people are highly prone to osteoartheritis. Considerable growth in osteoartheritis treatment in India is evident now a days. Initially Osteoartheritis was considered just a wear and tear in joint, which now getting more significant approach to treat the disease. Osteoarthritis is the main cause of joint pain both in animals and humans.  Natural cartilage regeneration is very limited and no current drug therapies are curative, but rather look to reduce the symptoms associated with the degeneration. More recently, the use of embryonic stem cell therapy for the treatment of artheritis, especially osteoartheritis.

The symptoms of osteoartheritis vary quite diversely, however few of the common traits of the disease include

Limited range of motion or stiffness 

Clicking or cracking sound when a joint bends

Mild swelling around a joint

Many people believe that the effects of osteoarthritis are inevitable, so they don’t do anything to manage it, however Osteoartheritis treatment in India through stem cell therapy is gaining awareness and successful upward trend in the curing the disease.

Joint aspiration, MRI and X ray are the modes through which one can test if he/she is suffering from or a victim of Osteoartheritics.Traditonally , getting involved in physical activity, streching and weight management was considered to tackle the disease, but development in the stem cell therapy and successful result of effective and efficient implementation of the treatment has proven the potential of the mode of treatment.

The Future Of Liver Cirrhosis Treatment With Stem Cells

Liver diseases, which occur out of infections, or metabolic diseases as well as autoimmune diseases are fatal. Majority of the times, injury to the liver leads to excess scarring of the liver, which is called liver cirrhosis. In this kind of disease, the metabolic functionality and synthetic functionally of the liver is hampered and it also results in greater risk of liver cancer. In western countries this diseases is among the top fatal diseases and the deaths caused by such liver cirrhosis is also rising at a fast pace. Presently, liver transplantation is the only option available for Liver cirrhosis Treatment.

The problem with the conventional Liver cirrhosis Treatment option is the lack of donor organs, as the supply of donor organs is not able to match the increasing demand of organs for transplantation. Other than these, immunosuppression and rejection of donor organs are other complications associated with the traditional treatment options. This is why scientists and doctors across the globe are involved in constant research to develop regenerative treatment options for curing such dangerous disease.

Of late, Stem Cell therapy has progressed at a fast rate and discovery of pluripotent cells is one of the latest findings in the ongoing research. These put forward a promise of generation of unending cells like hepatocyte, which can be used for transplantation in some of the liver diseases. However, there are many challenges in the way of developing stem cell based Liver cirrhosis Treatment, as in this disease the architecture of the liver is disturbed drastically because of excessive collagen deposition. 

The cells, which functions in our liver are known as hepatocytes. When a liver is in healthy condition, these cells divides and multiply in number, as a result, new cells generate to take the place of damaged or dead cells in the liver. When the liver suffers some kind of injury, another kind of cells called the oval cells lends a hand to produce hepatocytes. However, in the case of severe injury to the liver, the process of repairing of damaged cells is affected and scarring of the liver happens. Traditional treatment options like transplantation are very expensive, so researchers are studying the safety, efficiency, and feasibility of Stem Cell therapy that utilize autologous MSCs (Mesenchymal Stem cells) as a possible Liver cirrhosis Treatment. A number of such studies being carried out in different parts of the world have demonstrated that such Stem Cell therapy was able to suppress liver inflammation and also showed improvement in scarring along with replenishment of hepatocytes. This has given a new hope for Liver cirrhosis Treatment in the time to come. In a few clinical trials of Stem Cell therapy, administration of mesenchymal stem cells has proved to be safe and bearable and also displayed positive results in patients suffering from liver cirrhosis.

In the time to come pluripotent stem cells or embryonic cells might be utilized for generating new hepatocytes in lab conditions and then will be transplanted back into the patient whose liver is not able to generate new hepatocytes. Researchers are also exploring another type of Stem Cell therapy where cells from the bone marrow of the patient will be used for repairing the injured liver tissues.