Saturday 3 September 2016

Stem Cells Treatment for Arthritis

Stem cells and its treatment modalities can definitely be the next possible treatment “on the go”! It has been noted by huge accumulated data that stem cells can definitely do wonders for treating many degenerative conditions such as arthritis.

Researchers worldwide are working hard to find out new innovative ways to infuse stem cells in the joints exhibiting the problem of arthritis. It has as well been tried to figure out, which type of stem cells can express more healing power in case of joint disorders such as arthritis.

Arthritis is known to be an auto immune joint disorder, wherein the cushioning material known to be a cartilage is destroyed by body’s own immune cells; due to which the fiction between two bones of the joints is increased considerably, leading to its pain. Accordingly, many different conditions associated with joint degeneration and arthritic pain has been evaluated.

Out of many different forms of arthritis, the most degenerative form, so far has been reported to be osteoarthritis. Whereas the most severe form of arthritic disorders is noted down as rheumatoid arthritis. It has been statistically analyzed that the most common group affected with the arthritic issues are age group in the range of 40-60. Some of the early bird symptoms, categorically noted for arthritis are chronic pain in the joints, muscles as well as bones. Reported evidences of morning stiffness and occasional swelling that can be reduced without medical applications.

Conventional treatments that are offered to arthritis are generally steroidal medicines that can minimize systemic inflammatory attacks, some physiotherapies and weight loss to reduce pressure on joints. Although, current treatments report no long term effectiveness; on the contrary over exposure of steroidal medicines has proven to be harmful.

With the scientific advancements, the clinical applications of stem cells have been widely reported with significant effectiveness, but without any adverse reaction. The upgraded technology has enabled scientists and medical professionals to isolated stem cells from many autologous as well as allogenic sources such as bone marrow, adipose tissues, etc. These stem cells are enriched and concentrated outside the body in a controlled environment to add on its effectiveness. Once ready, these stem cells are then re-infused back into the body directly into the joints. Technically, these stem cells are as well stimulated with patient’s own platelet rich plasma to stimulate them inside the body to promote production of many growth hormones; which can initiate the process of regeneration and repair of cartilaginous cells known to be chondrocytes.

The regeneration and repair of chondrocytes can possibly help to minimize the progression of its damage and reduce the pain associated with arthritis.

Thus, stem cells treatment for arthritis, has moved ahead to reach to many new avenues and successes through global clinical trials. Researchers are investigating many new ways to inject stem cells in the body to maximize its effectiveness with minimum manipulation. Although, the ultimate goal of many on-going studies is to evaluate safety and feasibility of stem cells and their applications in case of diseased conditions.


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Stem Cell Treatment A New Hope for Patients

Stem cells are the “natural resources” available throughout the life of an individual and are responsible to make over with body’s natural wear and tear, such as wound healing, organ repair in case of crisis, immune build up of an individual, etc.

Stem cells treatment for possible debilitating diseases has exceptionally become a new defined era in the field of medical science; through which we can save many struggling lives that are currently facing health stigma! Stem cells being our own cells can have access to entire body without any medical hurdles such as rejection, other opportunistic infections etc.

In order to understand, what difference these little wonders can bring in for a diseased individual; we need to first understand their underlying mechanism.

What are these stem cells?

Stem cells are the unique, inherent cells of the body; which show their first appearance after the union of the male and female gametes. These are the first cells that are formed in the eight celled stage, after fertilization and through repeated cellular divisions. These stem cells have the power to give rise to an entire human being through proper signalling pathways.

It has also been identified that at each stage, stem cell lose its potency to become cell of any lineage; according embryonic stem cells are the cells of highest potency i.e. they are capable to be any type of cells, on the contrary, adult stem cells are multipotent that can only be selectively differentiated.  

What is stem cells treatment?

Stem cells treatment is evident based scientific miracle, wherein the potential of stem cells, to give rise to any type of cell; can be exploited in a specific manner to treat variety of diseases linked with the cell degeneration such as live problems, neurodegenerative disorders, etc.

With the help of upgraded technology, it is possible to isolate stem cells from the abundant sources such as bone marrow, adipose tissue, etc. Once isolated, these stem cells can be enriched in the clean and controlled environment to increase number of stem cells; which can be confirmed with the help of characterization techniques. These enriched stem cells can thus be re-infused back in the body through unique route of administration.

Once inside the body, these stem cells can detect site of injury through their strong networking capacity. Once they find their home, these stem cells can stimulate various growth factors and immune cells to regenerate dead and damaged cells.

What type of diseases can be cured?

Stem cell treatment can be used to treat variety of degenerative diseases such as:

·         Neurodegenerative diseases
·         Metabolic disorders such as liver problems, diabetes, etc.
·         Cosmetic treatments such as anti-ageing treatments
·         Arthritis related issues

The potential of stem cells has been proven through large data accumulated by worldwide clinical trials and studies. So far, no adverse reaction has been reportedly noted in large clinical studies and findings. However, the effectiveness of stem cells treatment is observed to be different on different individuals.

Although, every new finding has to pass through stringent studies providing effective solutions and hence is always advisable to analyse the same through positive and negative effects.


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