Stem cells Treatments for Autism

The critical demand for effective treatment for children suffering from autism is increased in near future. In this regard, stem cells treatment for autism is much more of the easy choice, than it was often thought to be. One of the greatest breakthroughs that these stem cells might impose is a constant reminder of body’s innate ability to heal itself in the crisis.

Autism is not as such a deadly disorder, on the contrary in developing countries like India; very few people are aware of the fact that there children are suffering from this autistic. It is actually an umbrella term for wide variety of diseases ranging from mild to severe forms. Scientists have linked up the occurrence of the condition to various risk factors such as genetic abnormality, vaccine reaction, injury, exposure to heavy metals and pesticides during pregnancy and environmental allergies, etc. There are other unknown causes as well, which are yet to be confirmed.

More often, it has been observed that autistic child has difficulty in maintaining cognitive functions such as control, coordination, social interaction, concentration, etc. In this regard, hardcore research and clinical studies have increased the basic understanding of underlying mechanism. In autistic children, a connection between the brain and its abilities to perform cognitive functions has been observed to be halted due to neural degeneration or weakened neurons. Stem cells, due to their strong regeneration properties are reported to be integrating well with the microenvironment of the brain. These stem cells being anti-inflammatory in nature can prevent the initial inflammation of faulty immune system; secrete various growth factors, which can relevantly direct these stem cells to become resident tissue specific cells such as neurons in case of brain. These superior functions of stem cells are important for their potential applications in stem cells therapeutics for autism.

It has well to be noted that there cannot be guaranteed improvement for adult stem cells treatment to autism, however enough positive changes have been noted in children after getting infusion in stem cells treatment.

Explorations in the field of Stem Cell Treatment for Diabetes

Diabetes is one of the most dangerous diseases, as it stealthily attacks the body. People normally overlook the initial symptoms, but with time both type-1 and type-2 diabetes turns into a serious problem and can prove fatal for the patient. The degenerative consequences of this disease are primarily because of hypoglycemic events and hyperglycemia, which set off degenerative conditions. When it comes to treating degenerative diseases, stem cell treatment for diabetes is the option that seems the most suitable.

Researchers have come up with innovative autologous stem cell treatment to treat both kinds of diabetes. This kind of therapy deals with the root conditions like hyperglycemia as well as complications associated with it. Some recent trials have also shown that stem cell treatment for diabetes can also aid in curing Hypoglycemia, which can be very hazardous if suitable treatment is not administered in time. Researchers in India are also involved in clinical trials to develop safer stem cell treatment for diabetes in India.

Recently, researchers are examining Mesenchymal stem cells, which comes with differentiation as well as self-renewing capacity. This capability of differentiating into different cell types including vascular, cartilage, brain, bone, and other cells proves that these can also help in controlling diabetes mellitus. Further studies are being conducted to explore the potential of MSCs in treating diabetic neuropathy, cardiomyopathy, diabetic retinopathy, polyneuropathy, as well as wounds caused by diabetes.

Of late, many clinics have surfaced that provide stem cell treatment for diabetes in India. The main aim of giving a boost to stem cell treatment for diabetes in India is to provide prolonged life to Indian masses, to help in reducing the symptoms of both kinds of diabetes, along with preventing the risky complications like kidney failure, heart disease, and even blindness.

Earlier stem cell treatment was mainly prevalent in western or European countries, but now stem cell treatment even for type-1 diabetes is now available in India. Researchers in India are now trying to explore two major techniques to use stem cell for curing type-1 diabetes. The first one involves exploring the capacity of beta cells and the second involve cells supporting repair of beta cells in patients. 

Stem cells Treatments for Diabetes

In the developed countries, sedentary life styles, diet and other wrong adaptive habits can exact the toll of diabetes in millions of people; may be young as well as old. Over the period of time, research has unfolded many pages, which lead to better understanding of the mechanism but still the scarcity of effective treatment is troubling many medical practitioners. For decades now, researchers are making slow but steady development in the applications of stem cells treatment for diabetes.

Diabetes is basically categorized as the group of disorders that is deregulated by the body’s faulty immune system; leading to damaged insulin producing cells. This damage can alter the blood glucose metabolism, causing it to be accumulated in the blood. Due to long term exposure of this sweet blood to different functional organs, such as heart, kidney or vascular system; they can be damaged severely. Thus diabetes is a condition that can be asymptomatic in its initial phase but go bizarre in later part of its progression.

Conventionally, no treatment is available for the condition, except for some supportive treatment approach such as hormonal supplements, diet control, regular exercise and weight loss. People have to follow their schedule strictly to manage the symptoms for their rest of the lives. It has been estimated that each year more than 1500, whole pancreatic transplant take place with more than 85% success rate. However, the demand for organs outweighs their availability. Besides, to allow the body to accept the transplanted organ, the patient has to be on strong supplementation, which may risk his life by other opportunistic infections.

Scientists have worked hard on developing a potential stem cell treatment diabetes. Since own cells are destroyed in autoimmune diseases such as type 1 diabetes; more emphasize would be in regulating immunological cells to deny their access of destruction. Stem cells are the potent cells with the ability to differentiate into different cells types depending upon the requirement. Modern technology has allowed easy isolation of these cells from different organs such as bone marrow, adipose tissue, etc. and infused back at the specific sites after laboratory enrichment. These cells then reprogram immune cells, reduce the initial inflammation and regenerate weakened cells to restructure cellular system of the pancreas to make it functionally powerful.

Thus, after addressing various safety and feasibility issues in various clinical studies, it has been clear that stem cells are undoubtedly promising candidates for implementing stem cells based therapies as routine practices for diseases such as diabetes.

Stem Cell Therapy In India

In recent year stem cells and their power of regeneration has constantly been in news because of their potential and differentiation ability to develop. These potential applications are promising for treating variety of deadly, degenerative disorders, which cannot be cured completely with conventional treatment option. These applications of stem cells are still a debatable issue. People are more skeptical, still for their success and effectiveness. Sometimes, they are equipped with wrong information about this stem cells therapy. Probably they are still not able to differentiate between adult stem cells and embryonic stem cells.

Scientists have diverted their attention now to explore various different adult stem cells sources. This is the reason, why adult stem cells sources such as adipose tissues, dental pulp and bone marrow are being used very commonly without the hassles of ethical debate. These cells are supposed to be less controversial because of their easy availability and low risk associated with their isolation from host. Stem cells are the naïve, unique cells; which can differentiate into many new cells of different origin, depending upon their potency. No doubt adult stem cells are less potent as compared to embryonic stem cells but considering the other advantages in their applications; adult stem cells can definitely be scientist’s first choice for developing cell based therapies.

Right from the last decade, considerable advancement have been achieved in the field of regenerative medicine. Earlier scientists have to wait for not less than three weeks to reach to the conclusion, whereas now the scenario has changed completely due to the technology automation. Now days, results are out within an hour of the sample processing. Processing can as well be done directly at the point of care near the bedside of the patient, suffering from diseases. It has also been possible that these potential adult sources can be stored under controlled conditions to use whenever there is demand; as an individual’s healthcare security.

Stem cells therapy is found out to be very potent in diseases such as orthopaedics, neuromotor degeneration, cancers, autoimmune diseases, etc.

Thus, anecdotal evidences have proved that stem cells therapies considerable improvements can be noted in case of fatal conditions; for which conventionally no treatments can be offered.

Stem cells Treatments for ALS

The reported neurology journal have recently published a new exciting study on safety and efficacy of stem cells based therapy for devastating diseases such as ALS. The clinical studies have confirmed that stem cells have considerably slow down the progression of neuronal damage in ALS.

ALS or amyotrophic lateral sclerosis is an incurable disease; involving slow and progressive degeneration of motor neurons. Brain is the central processing organ of human body. It controls and coordinates with all the other organs with the passage of information from it through spinal cord. In case of ALS, due to neuronal damage; brain will not be able to pass on the information to different muscular organs of the body. Stem cells are known to be very promising candidates for maintaining the numbers of lost neurons.

Ongoing clinical studies have concluded that stem cells and their effective neuromuscular regeneration have slowed down the degradation to a considerable level. Scientists are trying to figure out different route of administration of cells. It has been observed that stem cells injected directly into the cerebrospinal fluid of the central nervous system are more effective than other routes. Once inside the body, these cells can easily reach to the site of injury due to the strong signalling and networking properties of these cells. Their anti-inflammatory characteristics can reduce the inflammation, secrete growth factors and can regulate immune cells to promote faster regeneration of tissue specific cells.

Currently, no conventional treatment is available for ALS. The only treatment that is been offered to ALS patients is physiotherapy, diet and positive attitude. However, along with these supplements stem cells infusion can be effective in slowing down the progression of the disease

Thus, scientists are more optimistic that in near future, a definitive treatment can be offered to ALS patients to slow down or stop the progression of the disease. It is believed that currently stem cells cannot be considered as a cure by any means but it can definitely be considered as the first step towards the cure.